I'd like to see radiation as an important feature included in the game. For example, you will need a geiger counter to see radiation levels. Otherwise, your characters will be poisoned and they will need to visit a doctor/wash the dust etc. off as soon as possbile. Similarly, in certain areas they will simply be fried.
Anti-radiation suits help, but not for long. For example, if there's an area which is heavily radiated (like a part of LA) your characters shouldn't stay there for no longer than 30 minutes in-game, or maybe certain buildings for no more than 5 minutes. You will also need to clean the radiation off as soon as possible (don't need to be since it sounds like tedious micromanagament).
Do you think this is a good idea? I think this could be another enemy to combat in LA outside robots and mutants. Of course this could put too much pressure on players...