I certainly hope that there will be cyborgs in the sequel. They always seemed like the next big threat, and I used to suspect that the mission that Charmaine said she'd have for the rangers in a couple of months would be to investigate where the Newmen come from. Because men and machines don't just merge all on their own. There would have to be some kind of facility for that somewhere. Or possibly some kind of 'doctor' cyborg who can function like an ambulant Auto-Doc. Though I guess it could be something in between: A temporary facility that can be set up and taken down on the fly, where cyborgs carry all the needed materials and equipment. Whatever it is, it would sure be interesting to investigate, because those cyborgs were hostile, dangerous and numerous. I wonder how they recruit their people? Volunteers? Abducted 'regular folks'? Mortally wounded combatants, left for dead by their enemies? Yup. It would be
very interesting to get to investigate them. I guess that we already know where those robotnappers get their machine parts.

Another thing that would be interesting would be a faction of mutants that aren't just hostile monsters. That doesn't mean that they'd have to be particularly
friendly though, only that they could be reasoned with. Wouldn't want a rerun of Vault City and Gecko, because that has already been done. Maybe the mutants could be the ones in charge of a high tech settlement, worried that regular humans would want to rob them of their birthright? And therefore they're properly paranoid? That would be new, because in all of Wasteland 1, it seemed as if mutants were only skulking around at the edges of society. (Except for the three-legged hooker and the Mutie Cuties, I suppose. Apparently
some mutants are quite popular!)